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Tap Water Contributions to Plasma Concentrations of Poly- and Perfluoroalkyl Substances (PFAS) in a Nationwide Prospective Cohort of U.S. Women

Quoted values stay tied to the cited study. Empty sections are gaps.

Summary

Archived household tap-water measurements. Linear and branched isomers remain distinct. Medians and interquartile ranges are for detected samples only. Plasma measurements and modeled contributions are excluded. PFDA and PFBS descriptive rows remain valid as printed, but the paper excludes these analytes from downstream analyses because of nondetection frequency (p3).

Key numbers

Source-reported values checked against the cited page of the filed PDF. Values are reported as printed, without conversion. These are selected records, not an exhaustive transcription.

analytevalueunitbasissource locationlimits and qualifiers
PFOA0.57 (0.33, 1.36)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, nPFOAAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFOA0.39 (0.17, 0.51)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, brPFOAAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFNA0.23 (0.13, 0.29)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, nPFNAAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFNA0.19 (0.10, 0.34)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, brPFNAAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFDA0.22 (0.19, 0.94)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, PFDAAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFBS0.20 (0.19, 0.25)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, PFBSAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFHxS0.51 (0.23, 1.43)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, nPFHxSAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFHxS0.44 (0.18, 0.99)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, brPFHxSAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFOS0.69 (0.29, 1.80)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, nPFOSAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).
PFOS0.94 (0.51, 2.04)ng/Lmedian (IQR), detected archived tap-water samples onlyPDF p3, Table 2, brPFOSAnalyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).

Evidence Fitness

Source classification: primary_measurement. MANIFEST tier: PRIMARY. This is a selected, bounded transcription, not an exhaustive extraction of every result in the paper. Each selected number has its own PDF page or table locator. Values for different matrices, isomers, statistics and aggregate assays are not interchangeable.

Methods (brief)

SPE and triple-quadrupole LC-MS/MS; target scope and isomer calibration in PDF pp2-3. EOF measured by combustion ion chromatography is a separate assay (p5).

Detection limits and censoring: Analyte-specific water LODs are in unstaged Table S3. Table 2 statistics use samples above LOD only; downstream analyses use ROS imputation (p3).

Limitations

Provenance notes

Citation metadata verified against PDF p1, title, author byline, journal citation or masthead, and DOI.. Article DOI appears in the supplied PDF and matches the MANIFEST case-insensitively. Original file: 2019_Hu_tap-water-contributions-to-plasma-concentrations.pdf. SHA-256: d76901c1fb80b7402839b138078f1af87bd467b91b0c226355b94515bad4d74a. Original MANIFEST remains in the copied packet; discrepancies are listed without modifying it. Commercial analyte synonyms, instrument brands and manufacturer names are generalized in authored index prose.

Wiki pages updated on ingest

Tap drinking water

PFBS

PFDA

PFHxS

PFNA

PFOA

PFOS